Suppressive Effect of Tranilast on Interleukin-5 Prolonged Eosinophils Survival via Apoptosis
نویسندگان
چکیده
منابع مشابه
Suppressive effect of tranilast on interleukin-5 prolonged eosinophils survival via apoptosis.
Tranilast has long been used clinically to treat allergic diseases such as bronchial asthma. To further clarify the antiinflammatory machanism, we examined the ability of tranilast to counteract the prolongation of eosinophil survival induced by interleukin (IL)-5. Tranilast reduced the IL-5 prolonged survival of eosinophils at the concentration range of 30 microg/ml to 100 microg/ml. The DNA e...
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ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 2001
ISSN: 0021-5198
DOI: 10.1254/jjp.86.130